A gloomy outlook in May has turned into a potential $190 million future for Travere Therapeutics’ late-stage kidney asset.

Barely a week after announcing its intent to debut on the London Stock Exchange, Oxford Nanopore Technologies has locked down an investor willing to snap up about half of the shares on offer.

IASO Biotherapeutics bagged a hefty $108 million to fuel a teeming pipeline of cell therapies and antibodies for cancer and autoimmune disease. The series C round brings the company’s total raised to more than $178 million.

Amolyt Pharma has secured $80 million in financing from the likes of Novo Holdings and comes just a week after moving forward with a PeptiDream collaboration.

Deciphering the inner workings of the brain to get to the root of neurological conditions like Parkinson’s disease and multiple sclerosis is a lot like translating ancient writing systems into our modern languages—but the aptly named Rune Labs is on the case.

Francis Medical’s thermal water vapor ablation technology is picking up steam—literally and figuratively. The technology heats sterilized water into steam, which is then directed at tumors via a catheter to kill only cancerous cells while preserving the surrounding tissue.

Biosplice Therapeutics is attempting to clear its late-stage knee osteoarthritis treatment after other biopharmas have reached snags in the past year, and it now has $140 million worth of confidence with a partner in China.

Backed by a treatment-tuning platform, Allay Therapeutics is giving pain relief a major upgrade. Rather than relying on drugs repeatedly administered by capsule or IV to find their way to the point of pain, Allay’s analgesics are implanted directly into the surgical site and, thanks to slow-dissolving biopolymers, can provide post-op relief for several weeks.

Tyra Biosciences is the latest biotech to rake in an upsized IPO. Its $172.8 million deal will push three programs targeting drug-resistant cancers into the clinic.

Though Mesa Laboratories has spent much of its lifetime working behind the scenes, manufacturing software and supplies used to help healthcare providers, medical device makers and life sciences labs run smoothly, the Colorado-based company is ready for its moment in the spotlight.