CRISPR offers genetic clues to Alzheimer’s in brain’s cleaning crew

Microglia clear out the brain’s cellular debris and play a central role in maintaining the health of neurons. Changes in these special immune cells could act as potential drivers of brain diseases such as Alzheimer’s disease. Now, a research team led by the University of California, San Francisco (UCSF) has identified genetic regulators of microglia’s disease states.

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