Washing out WASH protein complex drives inflammation in mice

Neutrophils are the mercenaries of the immune system, but sometimes they’re messy fighters. The antimicrobial molecules they use as weapons don’t just knock out pathogens—in some cases, they damage healthy cells, too. When chronic or excessive, this activity is thought to be one of the mechanisms behind inflammatory conditions like sepsis, arthritis, atherosclerosis and some cancers, just to name a few.

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